83
Participants
Start Date
March 16, 2025
Primary Completion Date
March 16, 2026
Study Completion Date
March 16, 2027
Fasudil hydrochloride and PD1 inhibitor combined with androgen deprivation therapy
On the 1st to 5th day, Fasudil hydrochloride (10mg of fasudil hydrochloride) was treated, and on the 5th day, PD-1 monoclonal antibody (triprilizumab, 3mg/kg, intravenous drip) was treated. The treatment was repeated every 21 days for a total of 4 times
Placebo combined with androgen deprivation therapy
Days 1 to 5 were treated with placebo (0.9% sodium chloride 10mg), and days 5 were treated with placebo (0.9% sodium chloride 3mg/kg). The treatment was repeated every 21 days for a total of 4 times.
radical prostatectomy
Radical prostatectomy was performed 3 weeks (±7 days) after the treatment cycle
baotai Liang
OTHER