Standard Optimization of Stem Cells in Parkinson's Disease and Atypical Parkinsonism

"1. Participant's blood is drawn at the start of each visit.~2. Bone marrow aspirate is drawn from the posterior aspect of the pelvis and is subsequently harvested and processed.~3. The following procedures are administered in a crossover design (Day 0 and 6 months):~ * Intranasal bone marrow aspirate administration (INA BMAC) OR Sham INA~ * Intravenous bone marrow aspirate administration (IV BMA) OR Sham IVA~4. At 12 months, all participants receive IV BMA + INA BMAC"