Impact of NMES, Aerobic, and Resistance Exercise on Glycemic Control in Older Adults With Type 2 Diabetes

NANot yet recruitingINTERVENTIONAL
Enrollment

105

Participants

Timeline

Start Date

May 1, 2025

Primary Completion Date

May 1, 2026

Study Completion Date

May 1, 2026

Conditions
Type 2 Diabetes Mellitus (T2DM)
Interventions
DEVICE

Neuromuscular Electrical Stimulation (NMES)

Participants will receive NMES application for 30 minutes, three times a week, over a period of 12 weeks. The sessions will be supervised by a physiotherapist. Large muscle groups (quadriceps) will be used, with the following current parameters: frequency of 5 Hz, pulse width of 400 μs, 4 seconds of stimulation (on) for 12 seconds of rest (off), and intensity adjusted to the maximum tolerable level for the patient. These parameters are based on studies that have shown significant improvements in glycemic control and insulin sensitivity, especially in older adults with type 2 diabetes.

BEHAVIORAL

Aerobic and resistance exercise

This group will participate in an exercise program combining aerobic and resistance activities, performed three times per week for 12 weeks. The activities will be adapted to the participants' physical capabilities and supervised by a physiotherapist. The program follows the international recommendations and it includes a 5-minute warm-up with flexibility exercises, 20 minutes of aerobic exercise at 60-75% of maximum heart rate or moderate perceived exertion, 20 minutes of resistance exercise at 50-70% of one-repetition maximum (1RM) focusing on large muscle groups (10-15 repetitions per exercise, 1-3 sets), and a 5-minute cool-down with static stretching and breathing exercises for relaxation.

BEHAVIORAL

Health literacy education

Participants will receive educational sessions on diabetes management, the role of exercise in glycemic control, and strategies to enhance adherence to physical activity.

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

University of Salamanca

OTHER

collaborator

Escola Superior de Tecnologia da Saúde de Coimbra

OTHER

collaborator

Instituto Piaget

OTHER

lead

Carlos Tavares

OTHER

NCT06856720 - Impact of NMES, Aerobic, and Resistance Exercise on Glycemic Control in Older Adults With Type 2 Diabetes | Biotech Hunter | Biotech Hunter