150
Participants
Start Date
March 1, 2025
Primary Completion Date
December 31, 2025
Study Completion Date
December 31, 2026
Comprehensive weight loss
Shared Medical Appointments
Enhanced lifestyle changes
Subjects will also be referred to an exercise physiologist for a personalized physical activity program. Physical Activity and Exercise will be discussed during SMAs as well and individually as needed for exercise progression The participants exercise prescription will be individualized based on an initial assessment. Exercise duration and progression will be recommended at the discretion of staff and exercise physiologist. The exercise program will be structured but flexible, which means patients can substitute group exercises with individual exercise if necessary, following the FITT-VP format (frequency, intensity, time, type, volume and progression). Patients can reduce exercise frequency if the duration is prolonged, or intensity is increased. Investigators will encourage patients to use Cleveland Clinic gyms across the enterprise.
Phentermine-Topiramate
Medication for chronic weight management (Rx)
Naltrexone-Bupropion Combination
Medication for chronic weight management (Rx)
Orlistat
Medication for chronic weight management (Rx)
RECRUITING
Cleveland Clinic, Cleveland
The Cleveland Clinic
OTHER