NCT06854029 - NOTRE: Optimizing Long-Acting Pre-Exposure Prophylaxis and Medications for Opioid Use Disorder Interventions in Carceral Settings | Biotech Hunter

Enrollment

300

Participants

Timeline

Start Date

November 30, 2025

Primary Completion Date

December 31, 2029

Study Completion Date

June 30, 2030

Conditions

HIV InfectionsOpioid Use DisorderIncarceration; Lens

Interventions

DRUG

Cabotegravir Injection

Long-acting injection (LAI) Prep + X-RB treatment initiated in jail or prison.

DRUG

Cabotegravir Pill

Oral PrEP + SL-B treatment initiated in jail or prison.

DRUG

Buprenorphine injection

Long-acting injection (LAI) Prep + X-RB treatment initiated in jail or prison.

DRUG

Buprenorphine Pill

Oral PrEP + SL-B treatment initiated in jail or prison.

Trial Locations (1)

Duke University Medical System, Durham