Zanubrutinib, Obinutuzumab, and Sonrotoclax in Previously Untreated Patients With CLL or SLL

PHASE2RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

May 16, 2025

Primary Completion Date

March 1, 2028

Study Completion Date

March 1, 2030

Conditions
Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma (SLL)
Interventions
DRUG

Zanubrutinib

Bruton's Tyrosine Kinase (BTK) inhibitor

DRUG

Sonrotoclax

B-cell lymphoma 2 (BCL2) protein inhibitor

DRUG

Obinutuzumab

Anti-CD20 monoclonal antibody

Trial Locations (2)

10065

NOT_YET_RECRUITING

Memorial Sloan Kettering Cancer Center, New York

02114

RECRUITING

Massachusetts General Hospital, Boston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

BeOne Medicines

INDUSTRY

lead

Massachusetts General Hospital

OTHER

NCT06849713 - Zanubrutinib, Obinutuzumab, and Sonrotoclax in Previously Untreated Patients With CLL or SLL | Biotech Hunter | Biotech Hunter