An Efficacy and Safety Study With Integrated Pharmacokinetics (PK) and Pharmacodynamic (PD) Assessment to Compare the Proposed Ocrelizumab Biosimilar CYB704 and Ocrevus in Participants With Relapsing Multiple Sclerosis (RMS)

PHASE3RecruitingINTERVENTIONAL
Enrollment

518

Participants

Timeline

Start Date

June 10, 2025

Primary Completion Date

May 14, 2027

Study Completion Date

October 14, 2029

Conditions
Relapsing Multiple Sclerosis
Interventions
BIOLOGICAL

CYB704

Intravenous Infusion

BIOLOGICAL

Ocrevus-EU

Intravenous Infusion

BIOLOGICAL

Ocrevus-US

Intravenous Infusion

Trial Locations (22)

32174

RECRUITING

Sandoz Investigational Site, Ormond Beach

32751

RECRUITING

Sandoz Investigational Site, Maitland

Unknown

RECRUITING

Sandoz Investigational Site, Banja Luka

RECRUITING

Sandoz Investigational Site, Sarajevo

RECRUITING

Sandoz Investigational Site, Pleven

RECRUITING

Sandoz Investigational Site, Plovdiv

RECRUITING

Sandoz Investigational Site, Sofia

RECRUITING

Sandoz Investigational Site, Varaždin

RECRUITING

Sandoz Investigational Site, Zagreb

RECRUITING

Sandoz Investigational Site, Rustavi

RECRUITING

Sandoz Investigational Site, Tbilisi

RECRUITING

Sandoz Investigational Site, Shtip

RECRUITING

Sandoz Investigational Site, Skopje

RECRUITING

Sandoz Investigational Site, Bydgoszcz

RECRUITING

Sandoz Investigational Site, Katowice

RECRUITING

Sandoz Investigational Site, Lodz

RECRUITING

Sandoz Investigational Site, Nowa Sól

RECRUITING

Sandoz Investigational Site, Poznan

RECRUITING

Sandoz Investigational Site, Warsaw

RECRUITING

Sandoz Investigational Site, Zabrze

RECRUITING

Sandoz Investigational Site, Belgrade

RECRUITING

Sandoz Investigational Site, Niš

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Sandoz

INDUSTRY