Evaluation of the Safety and Efficacy of Live ASCs in the Treatment of Diabetic Foot (FOOTCELL)

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

105

Participants

Timeline

Start Date

March 8, 2025

Primary Completion Date

February 28, 2027

Study Completion Date

August 1, 2027

Conditions
Diabetic Foot Ulcer
Interventions
BIOLOGICAL

A - Allogenic ADSC cells in fibrin solution - two times administration ADSC/ASC

ADSC/ASC will be administered twice, at two-week intervals - during V0 and V2 visits The first dose will be administered one week after the randomisation visit. Control visits after administration will be performed every week, up to V6 visit (up to 6 weeks after V0).

BIOLOGICAL

B - Allogenic ADSC cells in fibrin solution - one time administration of ADSC/ASC, one time of placebo

ADSC/ASC will be administered once, at the time of the second application patients will receive a placebo - during V0 and V2 visits The first dose will be administered one week after the randomisation visit. Control visits after administration will be performed weekly, up to V6 visit (up to 6 weeks after V0)

OTHER

C - Standard care in diabetic foot ulcer with aplication of fibrin gel to cover wound surface.

Placebo will be administered twice, at two-week intervals - during V0 and V2 visits The first dose will be administered one week after the randomisation visit. Control visits after administration will be performed every week, up to V6 visit (up to 6 weeks after V0).

Sponsors
All Listed Sponsors
collaborator

Medical Research Agency, Poland

OTHER_GOV

lead

Medical University of Warsaw

OTHER

NCT06843122 - Evaluation of the Safety and Efficacy of Live ASCs in the Treatment of Diabetic Foot (FOOTCELL) | Biotech Hunter | Biotech Hunter