Pain with Differing Intraperitoneal Washes At the End of Laparoscopic Gynecologic Surgery

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

96

Participants

Timeline

Start Date

March 31, 2025

Primary Completion Date

February 28, 2026

Study Completion Date

March 31, 2027

Conditions
Laparoscopic Adnexal Surgery
Interventions
OTHER

Normal Saline (0.9% NaCl)

"Women will undergo planned, laparoscopic gynecologic surgery with an intraperitoneal wash of 20 mL of saline (standard) at the end of the operation, prior to insufflation, release, and skin closure.~The wash will be instilled into the peritoneal cavity and the surgical area (over the vaginal cuff and along the bilateral pelvic sidewalls to the paracolic gutters).~All participants will rate their pain using a Visual Analogue Scale (VAS). The VAS is a numerical rating system where the scores range from zero (0) to ten (10), with zero indicating 'no pain at all' and ten indicating 'the worst possible pain'.~Participants will be asked to rate their current level of pain and also report their current dosage of pain medication at the following intervals: pre-operatively, 2 hours post-operatively, and 24 hours post-operatively."

DRUG

Marcaine hydrochloride without epinephrine 0.5%

Women will undergo planned, laparoscopic gynecologic surgery with an intraperitoneal wash of 20 mL Marcaine hydrochloride (bupivacaine) without epinephrine 0.5% (the comparator) at the end of the operation, prior to insufflation, release, and skin closure. The wash will be instilled into the peritoneal cavity and the surgical area (over the vaginal cuff and along the bilateral pelvic sidewalls to the paracolic gutters). All participants will rate their pain using a Visual Analogue Scale (VAS). The VAS is a numerical rating system where the scores range from zero (0) to ten (10), with zero indicating 'no pain at all' and ten indicating 'the worst possible pain'. Participants will be asked to rate their current level of pain and also report their current dosage of pain medication at the following intervals: pre-operatively, 2 hours post-operatively, and 24 hours post-operatively.

Trial Locations (1)

38163

University of Tennessee Health Science Center, Memphis

All Listed Sponsors
lead

University of Tennessee

OTHER