The Impact of Ultrasound-Guided Superficial and Deep Paravertebral Nerve Blocks at the Superior Costotransverse Ligament on Hemodynamics During the Induction Phase of Thoracoscopic Lung Lobectomy: A Multicenter, Double-Blind, Randomized Controlled Trial

NARecruitingINTERVENTIONAL
Enrollment

168

Participants

Timeline

Start Date

May 25, 2025

Primary Completion Date

June 25, 2026

Study Completion Date

June 30, 2026

Conditions
Thoracic Paravertebral BlockAnesthesia InductionHypotension on Induction
Interventions
OTHER

SCTL superficial plane block

The purpose of this study was to evaluate whether thoracic paravertebral nerve block performed on superficial SCTL (puncture needle did not break SCTL) was more beneficial to maintaining hemodynamic stability during the induction period of thoracoscopic lobectomy compared with SCTL deep plane (puncture needle break SCTL). We performed an ultrasound-guided paravertebral nerve block while keeping the puncture needle did nit to break through the SCTL. In 20 patients who required CT (3D) imaging to observe drug diffusion 30min after nerve block, cold stimulation was used 30min after the procedure to assess the degree of sensory loss, including the anterior chest wall (midclavian line), lateral chest wall (posterior axillary line), and posterior chest wall (paravertebral area).

OTHER

SCTL deep plane block group

Ultrasound-guided thoracic paravertebral nerve block was routinely performed. SCTL was broken by a puncture needle during the ultrasound-guided thoracic paravertebral block. In 20 patients who required CT (3D) imaging to observe drug diffusion 30min after nerve block, cold stimulation was used 30min after the procedure to assess the degree of sensory loss, including the anterior chest wall (midclavian line), lateral chest wall (posterior axillary line), and posterior chest wall (paravertebral area).

Trial Locations (1)

210006

RECRUITING

Nanjing First Hospital, Nanjing

All Listed Sponsors
collaborator

Geriatric Hospital of Nanjing Medical University

OTHER

collaborator

Dushu Lake Hospital Affiliated to Soochow University

OTHER

collaborator

Huai'an First People's Hospital

OTHER

collaborator

Yancheng First People's Hospital

OTHER

lead

Nanjing First Hospital, Nanjing Medical University

OTHER

NCT06841822 - The Impact of Ultrasound-Guided Superficial and Deep Paravertebral Nerve Blocks at the Superior Costotransverse Ligament on Hemodynamics During the Induction Phase of Thoracoscopic Lung Lobectomy: A Multicenter, Double-Blind, Randomized Controlled Trial | Biotech Hunter | Biotech Hunter