CD123-CD16-NK Cells Immunotherapy for AML

PHASE1RecruitingINTERVENTIONAL
Enrollment

9

Participants

Timeline

Start Date

February 21, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
AML (Acute Myelogenous Leukemia)NK CellCD123+ Acute Myeloid Leukemia
Interventions
DRUG

Donor-derived CD123-CD16 bispecific antibody-modified NK cells

Patients enrolled sequentially received varying doses of NK cell infusions. The first three patients received 1×10⁷ cells/kg, the next three received 2×10⁷ cells/kg, and the final three received 4×10⁷ cells/kg.

Trial Locations (1)

100853

RECRUITING

Chinese PLA General Hospital, Beijing

All Listed Sponsors
collaborator

Chinese PLA General Hospital

OTHER

lead

Chunji Gao

OTHER