Long Term Efficacy and Safety of TMS Targeting Cerebellum to Treat DRE

NANot yet recruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

March 28, 2025

Primary Completion Date

March 27, 2027

Study Completion Date

March 27, 2027

Conditions
Drug-resistant EpilepsyTranscranial Magnetic Stimulation
Interventions
DEVICE

cTBS

"Continuous θ-burst stimulation (cTBS) is characterized by plexus stimulation. The stimulation intensity was 80% resting motor threshold (RMT) at 50Hz of intra plexus pulse while the frequency of inter plexus pulse is 5Hz, the duration was 40s, and the number of stimulation pulses was 600. Two groups of stimulation were repeated in each cerebellar dentate nucleus with an interval of 5 min in each group.~1. Enhanced phase:participants received cTBS treatment for a total of 5 times a week for 2 weeks;~2. Consolidation phase:participants received cTBS treatment for a total of twice a week (at least 24 hours apart) for 8 weeks;~3. Maintenance phase:participants received cTBS treatment for a total of once a week for 8 weeks."

Trial Locations (1)

710032

Xijing Hospital, Xi'an

All Listed Sponsors
lead

Xijing Hospital

OTHER

NCT06832813 - Long Term Efficacy and Safety of TMS Targeting Cerebellum to Treat DRE | Biotech Hunter | Biotech Hunter