Phase I Clinical Study of AV-1959R: Abeta-targeting Anti-Alzheimer's Vaccine

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

June 12, 2024

Primary Completion Date

October 31, 2025

Study Completion Date

October 31, 2025

Conditions
Alzheimer DiseaseAlzheimer Disease (AD)Alzheimers Disease Prevention
Interventions
BIOLOGICAL

AV-1959R (Abeta vaccine)

AV-1959R is an investigational adjuvanted vaccine designed to induce a targeted immune response against beta-amyloid (Aβ) to support the primary prevention of Alzheimer's disease and the treatment of asymptomatic preclinical Alzheimer's disease. It is administered intramuscularly (IM) at doses of 100 µg or 300 µg on Weeks 0, 4, and 14, in combination with the adjuvant.

Trial Locations (1)

Unknown

Arvax, Adelaide

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Arvax

UNKNOWN

lead

Nuravax, Inc.

INDUSTRY