Neoadjuvant Chemoradiotherapy With or Without Concurrent Azeliragon in Patients With Newly Diagnosed Glioblastoma

EARLY_PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

October 31, 2025

Primary Completion Date

January 31, 2029

Study Completion Date

July 31, 2030

Conditions
Glioblastoma
Interventions
DRUG

Azeliragon

Provided by Cantex Pharmaceuticals

DRUG

Temozolomide

Standard of care.

RADIATION

Radiation therapy

Standard of care.

PROCEDURE

Surgery or LITT

Standard of care surgical resection or laser interstitial thermal therapy (LITT).

Trial Locations (1)

63110

Washington University School of Medicine, St Louis

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Cantex Pharmaceuticals

INDUSTRY

lead

Washington University School of Medicine

OTHER