Feasibility Study Assessing the Effect of Carbidopa/levodopa Ratio on Orthostatic Hypotension in Multiple System Atrophy - Parkinsonian Type and Parkinson Disease.

PHASE1/PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

May 31, 2025

Primary Completion Date

November 30, 2026

Study Completion Date

November 30, 2026

Conditions
Multi-system Atrophy - Parkinsonian TypeOrthostatic Hypotension, DysautonomicParkinson Disease
Interventions
DRUG

Administration of Carbidopa/levodopa

Participants will perform beat-by-beat orthostatic tests (Schellong tests) before and after intake of single doses of carbidopa:levodopa combinations at 3 different ratios

Trial Locations (1)

1012

Centre Hospitalier Universitaire Vaudois, Lausanne

All Listed Sponsors
lead

Julien Bally

OTHER

NCT06831500 - Feasibility Study Assessing the Effect of Carbidopa/levodopa Ratio on Orthostatic Hypotension in Multiple System Atrophy - Parkinsonian Type and Parkinson Disease. | Biotech Hunter | Biotech Hunter