Use of Phage Therapy for Treatment of a Periprosthetic Joint Infection

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

1

Participants

Timeline

Start Date

February 22, 2024

Primary Completion Date

February 28, 2025

Study Completion Date

February 28, 2025

Conditions
Periprosthetic Joint Infection
Interventions
BIOLOGICAL

Phage (Cytophage Technologies)

"Our phage is a new type of investigational treatment for bacterial infections. Our lytic, monophage preparation was provided by Cytophage Technologies and underwent rigorous testing to ensure final product potency (7 x 10\^9 PFU/dose), purity, fidelity, and safety; laboratory tests demonstrate phage in vitro efficacy against the S. epidermidis strain.~Phage prepared in injection-grade saline will be given via two routes: a) intravenously twice daily, and concomitantly, b) intraarticularly twice daily, for a total duration of 14 days."

Trial Locations (1)

K1Y 4E9

Ottawa Hospital Research Institute, Ottawa

All Listed Sponsors
collaborator

Cytophage Technologies Inc.

UNKNOWN

lead

Ottawa Hospital Research Institute

OTHER