Transcutaneous Electrical Stimulation for Apnea Detected by Capnography

NARecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

April 10, 2025

Primary Completion Date

March 1, 2026

Study Completion Date

December 30, 2026

Conditions
Respiratory DepressionOpioids
Interventions
DEVICE

transcutaneous electrical nerve stimulation (TENS)

"A TENS 3000-unit, which is FDA and health Canada approved (Licence No.: 95655) and operated by a small 9V block battery will be used. Potential participants will receive a detailed written explanation of the TES protocol and a brief demonstration of how it works, including the feeling produced by the skin stimulator. Patient-specific TES thresholds will be determined after informed written consent for study participation is obtained. Surface electrode pads will be placed on the ventral surface of the forearm, and 1-Hz pulses will be gradually administered with an increase in current. Patients will be asked to report when they first feel the stimulation and when it becomes annoying. The milliamp current associated with these two levels of stimulation will be recorded on the participant's baseline data collection form. The annoying thresholds for all study participants will be used to deliver stimuli in response to respiratory depression in the PACU."

Trial Locations (2)

M4Y 1R6

ACTIVE_NOT_RECRUITING

Toronto General Hospital, Toronto

Unknown

RECRUITING

Toronto General Hospital, Toronto

All Listed Sponsors
collaborator

University Health Network, Toronto

OTHER

lead

University of Toronto

OTHER