NALIRIFOX Before Surgery for the Treatment of Borderline Resectable Pancreatic Ductal Adenocarcinoma, Nectar Trial

PHASE2RecruitingINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

March 1, 2027

Study Completion Date

March 1, 2027

Conditions

Borderline Resectable Pancreatic Ductal Adenocarcinoma

Interventions

PROCEDURE

Biospecimen Collection

Undergo blood sample collection

PROCEDURE

Computed Tomography

Undergo CT

DRUG

Fluorouracil

Given IV

DRUG

Irinotecan Sucrosofate

Given IV

DRUG

Leucovorin Calcium

Given IV

DRUG

Oxaliplatin

Given IV

PROCEDURE

Surgical Procedure

Undergo surgical resection

Trial Locations (1)

RECRUITING

Roswell Park Cancer Institute, Buffalo

All Listed Sponsors

lead

Roswell Park Cancer Institute

OTHER