44
Participants
Start Date
May 28, 2025
Primary Completion Date
December 31, 2026
Study Completion Date
March 31, 2029
Endoscopic variceal ligation (EVL)
"1. EVL for high-risk varices will be performed by experienced endoscopists, certified in gastroenterological endoscopy, within two weeks prior to the initiation of the Atezo/Bev.~2. A follow-up EGD will be conducted one week after the Atezo/Bev #3. If any of the following criteria are met, additional EVL will not be performed, and anticancer treatment will proceed two weeks later. Otherwise, an additional on-demand EVL session will be conducted:~ * The esophageal varices have improved to F1 or less.~ * The red color sign has disappeared.~3. On-demand EVL will be considered after 5th, and 7th consecutive doses of Atezo/Bev, with EGD follow-up performed to assess eligibility. The maximum number of EVL sessions is limited to three sessions."
RECRUITING
Liver cancer center, Asan Medical Center, Seoul
Lead Sponsor
Seoul National University Hospital
OTHER
Hanyang University
OTHER
Samsung Medical Center
OTHER
National Cancer Center, Korea
OTHER_GOV
Seoul National University Bundang Hospital
OTHER
Asan Medical Center
OTHER