60
Participants
Start Date
October 31, 2025
Primary Completion Date
December 31, 2026
Study Completion Date
December 31, 2026
Fisetin followed by Placebo
Fisetin 20 mg/kg per dose twice daily on two consecutive days for two consecutive weeks. Participants will return on day 14 for a blood draw followed by a 14-day wash-out. At the 4-week visit participants will receive a cross-over placebo-controlled dosing regimen to be taken twice daily on two consecutive days for two consecutive weeks.
Placebo followed by Fisetin
Placebo twice daily on two consecutive days for two consecutive weeks. Participants will return on day 14 for a blood draw followed by a 14-day wash-out. At the 4-week visit participants will receive a cross-over Fisetin 20 mg/kg per dose twice daily on two consecutive days for two consecutive weeks.
Atrium Health Wake Forest Baptist Hospital, Winston-Salem
The Ambrose Monell Foundation
UNKNOWN
Wake Forest University Health Sciences
OTHER