Pilot Study of Fisetin to Improve Fatigue Among Older Adult Cancer Survivors

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

October 31, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Fatigue
Interventions
DRUG

Fisetin followed by Placebo

Fisetin 20 mg/kg per dose twice daily on two consecutive days for two consecutive weeks. Participants will return on day 14 for a blood draw followed by a 14-day wash-out. At the 4-week visit participants will receive a cross-over placebo-controlled dosing regimen to be taken twice daily on two consecutive days for two consecutive weeks.

DRUG

Placebo followed by Fisetin

Placebo twice daily on two consecutive days for two consecutive weeks. Participants will return on day 14 for a blood draw followed by a 14-day wash-out. At the 4-week visit participants will receive a cross-over Fisetin 20 mg/kg per dose twice daily on two consecutive days for two consecutive weeks.

Trial Locations (1)

27157

Atrium Health Wake Forest Baptist Hospital, Winston-Salem

All Listed Sponsors
collaborator

The Ambrose Monell Foundation

UNKNOWN

lead

Wake Forest University Health Sciences

OTHER