Role of Medication in Making Urine Less Acidic as Part of Kidney Stone Prevention

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

January 1, 2026

Primary Completion Date

December 31, 2026

Study Completion Date

March 31, 2027

Conditions
Kidney Calculi
Interventions
DRUG

Potassium Citrate Extended Release Oral Tablet

In this crossover study, patients will serve as their own controls. Patients will receive slow-release potassium citrate (UroCit-K), potassium magnesium citrate (powder), or potassium magnesium citrate (tablets). The study period will last approximately 6 weeks for each participant. Patients will be instructed to take one form of potassium citrate for one week at a time followed by a washout period for one week. This process will be completed a total of three times as we seek to study the effects of three forms of potassium citrate.

All Listed Sponsors
lead

University of Texas Southwestern Medical Center

OTHER