The Effects of Henagliflozin on Glucose Fluctuation and Immunosenescence in Type 2 Diabetes Patients on Insulin Therapy

PHASE4RecruitingINTERVENTIONAL
Enrollment

64

Participants

Timeline

Start Date

July 14, 2025

Primary Completion Date

December 31, 2027

Study Completion Date

March 30, 2028

Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG

Henggliflozin

Upon enrollment, at Visit 1 (baseline), overnight fasting blood and urine samples will be collected, and glucose levels will be monitored for 3-5 days using a continuous glucose monitoring (CGM) system (Medtronic MiniMed). After the preliminary assessment, participants will receiveHenggliflozin 10 mg once daily by oral administration for up to 16 weeks.

OTHER

Placebo

Upon enrollment, at Visit 1 (baseline), overnight fasting blood and urine samples will be collected, and glucose levels will be monitored for 3-5 days using a continuous glucose monitoring (CGM) system (Medtronic MiniMed). After the preliminary assessment, participants will receive a placebo once daily by oral administration for up to 16 weeks.

Trial Locations (1)

200092

RECRUITING

Shanghai Jiaotong University School of Medicine, Xinhua Hospital, Shanghai

All Listed Sponsors
collaborator

Jiangsu Hengrui Pharmaceutical Co., Ltd.

INDUSTRY

lead

Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

OTHER