132
Participants
Start Date
May 1, 2025
Primary Completion Date
May 1, 2025
Study Completion Date
August 31, 2027
Amantadine (100mg) as add on therapy.
Amantadine will be administered at the dose of 100 mg t.i.d or b.i.d. (if t.i.d. is not tolerated) over 12 weeks, after a period of 3 weeks of titration.T he study treatment will be stopped after a dose decrease of 100 mg / day every 3 days.
Placebo
Placebo tablets will be also administered b.i.d. or t.i.d over 12 weeks after a period of 3 weeks of titration. Placebo tablets will be indistinguishable from amantadine ones.
CHU Toulouse, Toulouse
University Hospital, Toulouse
OTHER