NCT06816953View on ClinicalTrials.gov

Cartilage Biomarkers and HEAD-US Score in Severe Hemophilia A Patients Receiving FVIII Prophylaxis

NAEnrolling by invitationINTERVENTIONAL
Enrollment

19

Participants

Timeline

Start Date

April 1, 2024

Primary Completion Date

January 30, 2025

Study Completion Date

February 28, 2025

Conditions
Hemophilia A
Interventions
DIAGNOSTIC_TEST

HEAD-US

HEAD-US for evaluate haemophilic arthropathy in 6 joints. (Elbow, Knee, Ankle)

DIAGNOSTIC_TEST

Urinary carboxy-terminal cross linked telopeptide of type II collagen

Cartilage biomarker represent cartilage degradation

DIAGNOSTIC_TEST

Inflammatory markers

Inflammatory markers included CBC, Ferritin, ESR, CRP

Trial Locations (1)

10330

Pediatric Department, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok

All Listed Sponsors
lead

Chulalongkorn University

OTHER