rhTNK-tPA Thrombolytic Removal of Intraventricular Hemorrhage

PHASE1RecruitingINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

March 1, 2025

Primary Completion Date

May 1, 2025

Study Completion Date

June 1, 2025

Conditions
Intraventricular Hemorrhage
Interventions
DRUG

Low dose group

The calculated injection amount of tenecteplase (tenecteplase injection amount = volume of intraventricular hematoma × 0.009 mg/ml) was diluted to 1ml with sterile injection water, and administered via the EVD.

DRUG

Medium dose group

The calculated injection amount of tenecteplase (tenecteplase injection amount = volume of intraventricular hematoma × 0.018 mg/ml) was diluted to 1ml with sterile injection water, and administered via the EVD.

DRUG

High dose group

The calculated injection amount of tenecteplase (tenecteplase injection amount = volume of intraventricular hematoma × 0.027 mg/ml) was diluted to 1ml with sterile injection water, and administered via the EVD.

Trial Locations (1)

100070

RECRUITING

Beijing Tiantan Hospital, Beijing

All Listed Sponsors
lead

Beijing Tiantan Hospital

OTHER