Project neuroARTEMIS

NARecruitingINTERVENTIONAL
Enrollment

189

Participants

Timeline

Start Date

April 29, 2025

Primary Completion Date

May 31, 2028

Study Completion Date

December 31, 2028

Conditions
Stimulant UseHuman Immunodeficiency Virus (HIV)Depression
Interventions
BEHAVIORAL

ARTEMIS

The ARTEMIS intervention includes 5 sessions delivered individually over Zoom across 3 months. The intervention teaches 9 positive affect skills: noting and capitalizing on positive events, gratitude journaling, formal and informal mindfulness, positive reappraisal and problem solving coping skills training, focusing on personal strengths, setting achievable goals, and small acts of kindness. Each session consists of a didactic portion with in vivo skills practice, and participants are asked to complete daily home practice of the skills between sessions.

BEHAVIORAL

Contingency management for Antiretroviral (ARV) adherence

All participants will received the contingency management (CM) intervention to support ARV adherence. They will use the Spotlight by Scene Health platform, a HIPAA-compliant mHealth application for directly observed therapy, to upload videos of ART adherence. The app records and uploads time-stamped videos of medication doses, which staff verify asynchronously. Participants will be paid for each verified dose and receive a weekly bonus if they complete 6 doses.

Trial Locations (1)

27101

RECRUITING

Wake Forest University School of Medicine, Winston-Salem

All Listed Sponsors
collaborator

Florida International University

OTHER

collaborator

National Institutes of Health (NIH)

NIH

collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

Wake Forest University Health Sciences

OTHER