Efficacy and Safety of Early Initiation of Vericiguat in Heart Failure After Acute Myocardial Infarction

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

April 1, 2025

Primary Completion Date

June 30, 2026

Study Completion Date

December 30, 2026

Conditions
Heart FailureAcute Myocardial Infarction (AMI)Acute Heart Failure (AHF)
Interventions
DRUG

Vericiguat

Patients enrolled in the experimental group will receive 26 weeks of oral vericiguat on top of the standard treatment, with vericiguat at a dose of 2.5 mg once a day, doubled every fortnight to a maximum dose of 10 mg once a day at the end of week 6 of the visit, which will be maintained for the duration of the treatment.

Trial Locations (1)

400000

The First Affiliated Hospital of Chongqing Medical University, Chongqing

All Listed Sponsors
collaborator

The Second Affiliated Hospital of Chongqing Medical University

OTHER

collaborator

The First Affiliated Hospital of Chongqing Medical Universty

UNKNOWN

lead

Dongying Zhang

OTHER

NCT06812546 - Efficacy and Safety of Early Initiation of Vericiguat in Heart Failure After Acute Myocardial Infarction | Biotech Hunter | Biotech Hunter