Effect of Clove Oil and Menthol Lozenges on Post-extubation Sore Throat

EARLY_PHASE1Enrolling by invitationINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

January 25, 2025

Primary Completion Date

October 15, 2025

Study Completion Date

November 15, 2025

Conditions
Sore Throat
Interventions
BIOLOGICAL

Menthol lozenge

Patients in the menthol group will fill out the Patient introduction form, patient follow-up form, and numerical pain scale just before the first application. After 60 minutes after extubation, they will be asked to take the lozenge into their mouth without chewing or swallowing it and suck it, and the patient will be monitored until the lozenge is completely dissolved. After the first lozenge is finished, the patient follow-up form and numerical pain scale will be filled out. The second lozenge will be sucked 90 minutes after extubation. The third lozenge will be sucked 120 minutes after extubation and the patient follow-up form and numerical pain scale will be filled out.

BIOLOGICAL

Clove lozenge

Patients in the clove group will fill out the Patient introduction form, patient follow-up form, and numerical pain scale just before the first application. After 60 minutes after extubation, they will be asked to take the lozenge into their mouth without chewing or swallowing it and suck it, and the patient will be monitored until the lozenge is completely dissolved. After the first lozenge is finished, the patient follow-up form and numerical pain scale will be filled out. The second lozenge will be sucked 90 minutes after extubation. The third lozenge will be sucked 120 minutes after extubation and the patient follow-up form and numerical pain scale will be filled out.

OTHER

None-placebo

Before routine clinical procedures after surgery, the patients in the control group will fill out the Patient introduction form, Patient follow-up form, and Numerical pain scale. After 60 minutes after extubation; clinical procedures do not include any procedures or interventions and the patient follow-up form and Numerical pain scale will be evaluated. After 120 minutes after extubation; the patient follow-up form and numerical pain scale will be evaluated.

Trial Locations (2)

34147

Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul

Unknown

İstanbul Atlas University, Istanbul

All Listed Sponsors
collaborator

Bakirkoy Dr. Sadi Konuk Research and Training Hospital

OTHER_GOV

lead

Atlas University

OTHER

NCT06811051 - Effect of Clove Oil and Menthol Lozenges on Post-extubation Sore Throat | Biotech Hunter | Biotech Hunter