Phase II Clinical Study of Contezolid for the Treatment of Bone and Joint Tuberculosis

PHASE1/PHASE2Enrolling by invitationINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

January 31, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
TuberculosisBoneJoint
Interventions
DRUG

Contezolid

"This study intends to enroll 24 patients with bone and joint tuberculosis, who will be randomly divided into two groups: the contezolid monotherapy group and the linezolid monotherapy group. Patients will receive oral contezolid or linezolid monotherapy for 14 consecutive days, and data on treatment safety, pharmacokinetics, and preliminary efficacy will be collected before and after administration.~Study Medications:~Contezolid 800mg QD for 14 days; Linezolid 600mg QD for 14 days."

DRUG

Linezolid (LZD)

Linezolid 600mg QD for 14 days.

Trial Locations (1)

101149

Beijing chest hospital affiliated to Capital medical university, Beijing Tuberculosis & Thoracic Tumor Research Institute, Beijing

All Listed Sponsors
lead

Beijing Chest Hospital

OTHER