Examination of the Dynamic Relationships of Sleep, Physical Activity, and Circadian Rhythmicity With Neurobehavioral Heterogeneity in ADHD

RecruitingOBSERVATIONAL
Enrollment

200

Participants

Timeline

Start Date

June 17, 2025

Primary Completion Date

June 30, 2030

Study Completion Date

June 30, 2032

Conditions
Attention Deficit Hyperactivity Disorder (ADHD)SleepPhysical Activity
Interventions
BEHAVIORAL

Go/No-Go Task

A computerized test in which participants are presented with red and green spaceship stimuli. They are told to press the spacebar in response to green spaceships (80% of trials) and withhold their response to red spaceships (20% of trials).

BEHAVIORAL

Delay discounting task

Participants make decisions between smaller, immediate rewards and larger, delayed rewards. The amount of the immediate reward and delay time are manipulated to identify individual delay discounting curves, or how the reward value decreases as a function of delay.

BEHAVIORAL

Mirror Tracing Persistence Task

A computerized test in which participants trace a star line drawing with a computer cursor using a trackpad with reversed directional controls. There are increasing levels of difficulty with participants being told they could quit the task during the very hard third star that they try to trace.

BEHAVIORAL

Spatial Span

Participants are instructed to attend to a computer screen to keep track of the order in which a happy face stimuli appears in a sequence of boxes positioned on the screen. They are presented with 2 trials at each level of difficulty, increasing from 2 stimuli by 1 additional stimuli per trial until they respond incorrectly for both trials within a level. There are two task conditions, forward and backward span, with the participant responding in the reverse order that the stimuli were presented for backward span.

BEHAVIORAL

Stop Signal Task

A computerized test in which participants are presented with a right or left facing arrow and are instructed to press a response button indicating the direction of the arrow. On 25% of the trials, an auditory beep is presented (i.e., stop signal) following the onset of the arrow (i.e., go signal) and participants are instructed to withhold their response when they hear the stop signal.

BEHAVIORAL

Flanker task

A computerized test in which a group of arrows are presented on the screen with the central arrow (target) pointing in the same/opposite direction as the 4 surrounding arrows (flankers). Participants are instructed to respond as quickly and accurately as possible to the central target arrow.

Trial Locations (2)

21205

RECRUITING

Hugo W. Moser Research Institute at Kennedy Krieger, Baltimore

RECRUITING

Kennedy Krieger Institute, Baltimore

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

OTHER

NCT06810180 - Examination of the Dynamic Relationships of Sleep, Physical Activity, and Circadian Rhythmicity With Neurobehavioral Heterogeneity in ADHD | Biotech Hunter | Biotech Hunter