EXpanding Prenatal Cell Free DNA Screening Across moNogenic Disorders (EXPAND)

RecruitingOBSERVATIONAL
Enrollment

4,000

Participants

Timeline

Start Date

January 25, 2024

Primary Completion Date

November 30, 2025

Study Completion Date

February 28, 2026

Conditions
Single Gene NIPT
Interventions
DEVICE

Single-gene Noninvasive Prenatal Testing (sgNIPT)

Natera sgNIPT is intended for use in pregnant people whose 'fetus/ fetuses are identified as at increased risk for a single gene disorder when there is no reproductive partner (paternal) screening available or when there is positive reproductive partner screening, but prenatal diagnostic testing is not an option or when there is concern for a single-gene disorder in the fetus/ fetuses irrespective of carrier status (e.g., based on fetal ultrasound findings).

Trial Locations (18)

10022

RECRUITING

NYU Langone, New York

10029

RECRUITING

Icahn School of Medicine at Mount Sinai, New York

10065

RECRUITING

Weill Medical College of Cornell University, New York

11040

RECRUITING

Northwell (Northshore/LIJ), New Hyde Park

11530

RECRUITING

NYU Langone Hospital, Garden City

14642

RECRUITING

University of Rochester, Rochester

32806

RECRUITING

Orlando Health Inc. (Winnie Palmer Hsopital), Orlando

39216

RECRUITING

UMMC WH Univerity Center For Fetal Medicine, Jackson

77477

RECRUITING

PEDIATRIX Medical Services, Inc. Master + Houston, Stafford

77555

RECRUITING

University of Texas Medical Branch (UTMB), Galveston

78758

RECRUITING

Austin Maternal Fetal Medicine/St. Davids Healthcare, Austin

85304

RECRUITING

Valley Perinatal, Glendale

90048

RECRUITING

Cedars Sinai Prenatal Diagnosis Center, Los Angeles

RECRUITING

Center for Fetal Medicine and Womens Ultrasound, Los Angeles

94070

RECRUITING

Natera Inc, San Carlos

94158

RECRUITING

University of California San Francisco, San Francisco

08648

RECRUITING

Capital Health, Lawrenceville

08901

RECRUITING

Rutgers Robert Wood Johnson Medical School, New Brunswick

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Natera, Inc.

INDUSTRY