801
Participants
Start Date
February 10, 2025
Primary Completion Date
April 30, 2025
Study Completion Date
April 30, 2025
S. haematobium egg detection by single urine filtration
The urine samples of children participating in the initial screening will be tested with a single urine filtration by human microscopy.
S. haematobium egg detection by quintuple urine filtration
Five urine samples will be collected from children participating in the diagnostic study over five days. Each of the five urine samples collected per participant will be tested with a single urine filtration by human microscopy.
S. haematobium egg detection by artificial intelligence (AI) microscopy
The urine samples collected on Day 5 of the diagnostic study will be tested with artificial intelligence (AI) microscopy.
Haematuria assessment using reagent strips
The urine samples collected from children participating in the initial screening and in the diagnostic study, respectively, will be tested with reagent strips.
S. haematobium antigen detection by up-converting reporter particle-lateral flow circulating anodic antigen assay (UCP-LF CAA)
The urine samples collected on Day 5 of the diagnostic study will be tested with the up-converting reporter particle-lateral flow circulating anodic antigen assay (UCP-LF CAA).
S. haematobium DNA detection by recombinase polymerase amplification assay (RPA)
The urine samples collected on Day 5 of the diagnostic study will be tested with the recombinase polymerase amplification assay (RPA).
S. haematobium DNA detection by qPCR
The urine samples collected on Day 5 of the diagnostic study will be tested with qPCR
Public Health Laboratory - Ivo de Carneri (PHL-IdC), Chake Chake
Collaborators (1)
Public Health Laboratory Ivo de Carneri
OTHER
Enaiblers AB
INDUSTRY
Erasmus Medical Center
OTHER
Leiden University Medical Center
OTHER
Natural History Museum, United Kingdom
OTHER_GOV
Stefanie Knopp
OTHER