Understanding Perinatal Spinal Cord Injury

NAEnrolling by invitationINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

January 9, 2024

Primary Completion Date

January 31, 2027

Study Completion Date

January 31, 2027

Conditions
Perinatal Spinal Cord Injury
Interventions
OTHER

Activity-Based Recovery Training

ABRT uses task-specific training to improve neuromuscular capacity. ABRT will be tailored to participant presentation. Activity-Based Locomotor Training consists of stepping, standing, and sitting activities on a body weight support (BWS) treadmill using a harness and while overground. Therapists and trainers provide hands-on assistance for safety and kinematics. BWS is varied during sessions with a goal of optimal kinematics at the lowest BWS. Activities performed standing will focus on alignment incorporating static, active, and dynamic tasks. Activities performed during overground are based on neuromuscular capacity and appropriate developmental and functional levels. Principles of ABRT will be shared with parents/caregivers to foster activity in the home and community. Activity-Based Upper Extremity Training uses task-specific training of the trunk and upper extremities administered in sitting or standing via manual facilitation or support in a stander for best posture.

DEVICE

Transcutaneous Spinal Cord Stimulation

Transcutaneous Spinal Cord Stimulation (scTs) is a non-invasive stimulation administered over the skin using a modulated biphasic or monophasic waveform at 15-90Hz and a carrier frequency of 5-10kHz. Bouts of scTs at the cervical, thoracic, lumbar, and/or coccygeal level will be administered midline or just lateral to the spinous processes during activity-based recovery training.

Trial Locations (1)

40202

University of Louisville, Louisville

All Listed Sponsors
collaborator

Vanderbilt University

OTHER

collaborator

University of Leeds

OTHER

collaborator

Kentucky Spinal Cord and Head Injury Research Trust

UNKNOWN

lead

University of Louisville

OTHER