A Single-center, Open-label, Study Evaluating Safety and Pharmacokinetics of Single Doses of Zidebactam-Cefepime and Metronidazole Alone or in Combination.

(1) ZID-FEP 3g IV (ZID 1 g plus FEP 2 g) administered over 1 hour (h)

(2) metronidazole 0.5 g IV alone administered over 1 h

(3) metronidazole 0.5 g IV over 1 h, followed by ZID-FEP 3g IV over 1 h over 3 treatment periods separated by a 48 h washout period.