Anti-CEACAM5 ADC M9140 in Chinese Participants With Solid Tumors (PROCEADE-CRC-02)

PHASE1RecruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

December 20, 2024

Primary Completion Date

May 7, 2026

Study Completion Date

May 7, 2026

Conditions
Solid TumorsColorectal Cancer
Interventions
DRUG

M9140

M9140 will be administered every 3 weeks until progression, unacceptable toxicity, withdrawal of consent, or any criterion for withdrawal from the study. There will be 2 dose levels, if the low dose level is tolerated, then M9140 will be escalated to the high dose level.

Trial Locations (3)

Unknown

RECRUITING

Beijing Cancer Hospital, Beijing

RECRUITING

The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou

RECRUITING

The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou

All Listed Sponsors
collaborator

Merck KGaA, Darmstadt, Germany

INDUSTRY

lead

Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany

INDUSTRY