QUANTIFY: Quantitative Understanding of Advanced Novel Techniques for Imaging Fasciitis and Yielding Biomarkers

NARecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

May 22, 2025

Primary Completion Date

July 31, 2026

Study Completion Date

August 31, 2026

Conditions
Plantar FasciopathyAchilles TendinopathyControls
Interventions
DIAGNOSTIC_TEST

Clinical exam

An experienced physical therapist with expertise in dry needling will confirm study eligibility and complete a standard clinical exam for myofascial pain. Gold standard for diagnosing myofascial pain as defined by Travell and Simons will be used. The criteria for muscle trigger point (TrP) include: 1) a taut band of skeletal muscle that is tender to palpation, 2) sustained compression of the taut band reproduces or exacerbates the participant's symptoms. Healthy tissue is defined as no palpable taut band.

DIAGNOSTIC_TEST

Ultrasound imaging

Shear wave elastography and b-mode ultrasound imaging techniques will capture the biomechanical and structural profile of foot and ankle muscle on the involved side.

DIAGNOSTIC_TEST

Magnetic Resonance Imaging

T1rho and IDEAL sequences will be used to capture the biochemical and structural profile of foot and ankle muscles on the involved side

Trial Locations (1)

52242

RECRUITING

University of Iowa Health Care, Iowa City

All Listed Sponsors
collaborator

National Center for Complementary and Integrative Health (NCCIH)

NIH

collaborator

Rochester Institute of Technology

OTHER

lead

Ruth Chimenti

OTHER