The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery

PHASE4RecruitingINTERVENTIONAL
Enrollment

18,000

Participants

Timeline

Start Date

April 1, 2025

Primary Completion Date

July 31, 2028

Study Completion Date

July 31, 2028

Conditions
AnesthesiaSurgery With General AnesthesiaNoncardiac SurgeryHypotension During SurgeryAcute Kidney Injury (AKI)Myocardial Injury After Noncardiac Surgery (MINS)Vasopressor
Interventions
DRUG

Norepinephrine

Intravenous Norepinephrine for both infusion and bolus dosing

DRUG

Phenylephrine

Intravenous Phenylephrine for both infusion and bolus dosing

Trial Locations (2)

48109

RECRUITING

University of Michigan, Ann Arbor

94143

RECRUITING

University of California, San Francisco, San Francisco

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

collaborator

University of Michigan

OTHER

collaborator

Henry Ford Health System

OTHER

collaborator

University of Washington

OTHER

collaborator

University of Texas Southwestern Medical Center

OTHER

collaborator

Wake Forest University Health Sciences

OTHER

collaborator

University of Virginia

OTHER

collaborator

University of Maryland

OTHER

collaborator

Duke University

OTHER

lead

University of California, San Francisco

OTHER

NCT06802224 - The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery | Biotech Hunter | Biotech Hunter