Effects of Long-Acting GLP-1 (Glucagon-like Peptide-1) or Dual Incretin (GLP-1 and GIP [Glucose-dependent Insulinotropic Peptide]) Modulation on Gastric Motor Functions

PHASE4RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

January 31, 2028

Study Completion Date

March 31, 2028

Conditions
Obesity
Interventions
DRUG

Semaglutide

Both interventions are approved by FDA for the treatment of obesity and are administered by subcutaneous injection once per week

DRUG

Tirzepatide

Both interventions are approved by FDA for the treatment of obesity and are administered by subcutaneous injection once per week

DRUG

Placebo

Placebo administered by subcutaneous injection once per week.

Trial Locations (2)

55905

RECRUITING

Mayo Clinic in Rochester, Rochester

RECRUITING

Mayo Clinic Rochester, Rochester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Mayo Clinic

OTHER