Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

315

Participants

Timeline

Start Date

January 31, 2026

Primary Completion Date

June 30, 2026

Study Completion Date

September 30, 2026

Conditions
Trichuris Trichiura; InfectionHookworm InfectionAscaris Lumbricoides Infection
Interventions
DRUG

emodepside (BAY 44-4400)

Treatment with single dose of oral 15 mg emodepside

DRUG

Mebendazole 100 MG

Treatment with 100 mg mebendazole orally administered b.i.d. for 3 days

DRUG

similar placebo to mebendazole

Treatment with mebendazole similar placebo orally administered b.i.d. for 3 days

DRUG

matching placebo of emodepside

Treatment with single dose of oral emodepside matching placebo

Trial Locations (1)

Unknown

University of the Philippines Manila, Manila

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bayer

INDUSTRY

collaborator

Silicon Valley Community Foundation

OTHER

collaborator

University of the Philippines

OTHER

lead

Swiss Tropical & Public Health Institute

OTHER