Tributyrin Treatment in Mild Alzheimer Disease: Assessment of Butyric Acid Effects Via the Gut-Brain

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

156

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

September 1, 2026

Study Completion Date

September 2, 2027

Conditions
Alzheimer Disease (AD)
Interventions
DIETARY_SUPPLEMENT

tributyrin

Participants will receive 1 capsule per day for 12 weeks. Each capsule contains 450 mg of tributyrins. The capsules will have a gelatin coating. In the market, formulations are available with dosages ranging from 200 to 500 mg.

OTHER

Placebo

The placebo will consist of potato starch encapsulated under identical conditions to those used for the tributyrin capsules, ensuring adequate blinding of the study.

Trial Locations (1)

Unknown

Universidad de Almería, Almería

All Listed Sponsors
lead

Universidad de Almeria

OTHER