Non-Inferiority Study on MRNA-lncRNA Model in Low-Risk Triple-Negative Breast Cancer Patients

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

1,462

Participants

Timeline

Start Date

February 28, 2025

Primary Completion Date

August 31, 2028

Study Completion Date

July 31, 2031

Conditions
Triple-negative Breast Cancer
Interventions
DRUG

Docetaxel plus cyclophosphamide

Docetaxel (T) at a dose of 75 mg/m² was administered intravenously on Day 1 of each cycle, and Cyclophosphamide (C) at a dose of 600 mg/m² was administered intravenously on Day 1 of each cycle as well.

DRUG

Epirubicin, cyclophosphamide plus paclitaxel

Patients in the control group received the EC-P regimen chemotherapy, with a cycle length of 21 days, for a total of 8 cycles. The specific treatment was as follows: Epirubicin (E) at a dose of 90 mg/m² and Cyclophosphamide (C) at a dose of 600 mg/m² were administered intravenously on Day 1 of each cycle for the first 4 cycles. This was followed by Paclitaxel (P) at a dose of 80 mg/m², administered intravenously on Days 1, 8, and 15 of each cycle for the subsequent 4 cycles.

All Listed Sponsors
lead

Fudan University

OTHER