Effect of Transcutaneous Auricular Vagus Nerve Stimulation Application on Respiratory Functions in Stroke Patients

NARecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

August 5, 2025

Primary Completion Date

August 26, 2025

Study Completion Date

July 30, 2027

Conditions
HemiplegiaRespiratory Function Loss
Interventions
DEVICE

Transcutaneous Auricular Vagus Nerve Stimulation

TAVSS is an application system that uses an electrical transcutaneous stimulation device placed on the concha or tragus of the ear. Functional Magnetic Resonance Imaging studies have shown that stimulation of these areas activates the ipsilateral nucleus tractus solitarius (NTS) via vagal projections to the brainstem and forebrain. Unlike cervical vagus nerve stimulation, TAVSS utilizes a physiological pathway to activate the NTS and the dorsal motor nucleus, which subsequently sends impulses bilaterally to the heart surface via efferent cervical vagus nerves. Therefore, this technique eliminates the possibility of directly and asymmetrically stimulating cardiac motor efferent fibers, which could lead to adverse cardiac events. TAVSS combines advantageous qualities such as being non-invasive, cost-effective, convenient, and efficient.

Trial Locations (1)

34040

RECRUITING

Mediworld Medical Center Physical Therapy and Rehabilitation Department, Istanbul

All Listed Sponsors
lead

Fenerbahce University

OTHER

NCT06793800 - Effect of Transcutaneous Auricular Vagus Nerve Stimulation Application on Respiratory Functions in Stroke Patients | Biotech Hunter | Biotech Hunter