50
Participants
Start Date
August 5, 2025
Primary Completion Date
August 26, 2025
Study Completion Date
July 30, 2027
Transcutaneous Auricular Vagus Nerve Stimulation
TAVSS is an application system that uses an electrical transcutaneous stimulation device placed on the concha or tragus of the ear. Functional Magnetic Resonance Imaging studies have shown that stimulation of these areas activates the ipsilateral nucleus tractus solitarius (NTS) via vagal projections to the brainstem and forebrain. Unlike cervical vagus nerve stimulation, TAVSS utilizes a physiological pathway to activate the NTS and the dorsal motor nucleus, which subsequently sends impulses bilaterally to the heart surface via efferent cervical vagus nerves. Therefore, this technique eliminates the possibility of directly and asymmetrically stimulating cardiac motor efferent fibers, which could lead to adverse cardiac events. TAVSS combines advantageous qualities such as being non-invasive, cost-effective, convenient, and efficient.
RECRUITING
Mediworld Medical Center Physical Therapy and Rehabilitation Department, Istanbul
Fenerbahce University
OTHER