NCT06793488View on ClinicalTrials.gov

Anxiety During Abstinence in AUD

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

September 15, 2025

Primary Completion Date

August 30, 2029

Study Completion Date

August 30, 2029

Conditions
Alcohol Use Disorder
Interventions
DRUG

Disulfiram 250 mg

Disulfiram will be used in Participants with Alcohol Use Disorder only to facilitate abstinence.

DIAGNOSTIC_TEST

functional MRI

Participants will undergo fMRI scanning. Participants with alcohol use disorder will undergo scanning after 1 week and 3 months of disulfiram maintenance. Healthy volunteer participants will undergo scanning once.

Trial Locations (1)

10019

RECRUITING

Columbia University Irving Medical Center, New York

All Listed Sponsors
collaborator

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NIH

lead

Columbia University

OTHER