60
Participants
Start Date
February 1, 2025
Primary Completion Date
August 1, 2025
Study Completion Date
October 1, 2025
Placebo Capsule
Participants will receive an inert placebo capsule that matches the probiotic capsule in size, shape, and color. The placebo will be administered orally twice daily, starting 2 weeks before surgery and continuing for 2 weeks postoperatively.
Probiotic with Human Milk Oligosaccharides (HMO)
Participants will receive a dual-strain probiotic containing Human Milk Oligosaccharides (HMO) in capsule form. The probiotic will be administered orally twice daily, starting 2 weeks before surgery and continuing for 2 weeks postoperatively.
Parvizi Surgical Innovation, Philadelphia
Istanbul University Cerrahpasa, Istanbul
Acıbadem International Joint Center, Istanbul
Acibadem LABMED Laboratories, Istanbul
Acıbadem Mehmet Ali Aydınlar University, Istanbul
Thonburi Trang Hastanesi, Thailand
Acibadem University
OTHER
Acibadem Maslak Hospital
OTHER