TRACK-TBI Precision Medicine Part 3 - Option II

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

August 31, 2025

Primary Completion Date

May 31, 2026

Study Completion Date

October 31, 2026

Conditions
Traumatic Brain Injury
Interventions
DRUG

Cyclosporine (CsA)

Intravenous (IV) injection, loading dose of 2.5 mg/kg (diluted in 0.9% NaCl to a final volume of 50 ml) given over 2 hours, immediately followed by a continuous IV infusion of of 5 mg/kg/day (diluted in 0.9% NaCl to a final volume of 250 ml) for 3 days (72-hour).

DRUG

Placebo

"Intravenous (IV) injection of 0.9% NaCl with the same dosing strategy as CsA: loading dose given over 2 hours, immediately followed by a continuous IV infusion for 3 days (72-hour)."

Trial Locations (1)

94110

University of California, San Francisco, San Francisco

All Listed Sponsors
collaborator

U.S. Army Medical Research and Development Command

FED

lead

University of California, San Francisco

OTHER