Evaluating Informatics-assisted Immune-related Adverse Event Detection to Improve Registration Onto a Biorepository

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

June 17, 2025

Primary Completion Date

August 31, 2027

Study Completion Date

August 31, 2027

Conditions
MalignancyImmune Related Adverse Events
Interventions
OTHER

Informatics system for eligibility monitoring

A daily automated data query of eligible subjects will collect EHR data, and our informatics system will be run on these data behind our institution's secure firewall. The daily list of subjects identified by the informatics system as having a new irAE will be accessed by the Alliance irAE biorespository study team at Dana-Farber/Brigham Cancer Center for review.

OTHER

Standard eligibility monitoring

Reporting of an eligible event to the biorepository study staff by the treating clinician and EHR review by the study staff.

Trial Locations (2)

02115

RECRUITING

Brigham and Women's Hospital, Boston

RECRUITING

Dana-Farber Cancer Institute, Boston

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Brigham and Women's Hospital

OTHER

NCT06789601 - Evaluating Informatics-assisted Immune-related Adverse Event Detection to Improve Registration Onto a Biorepository | Biotech Hunter | Biotech Hunter