"Xijiang Project Screening Cohort for NPC"

Active, not recruitingOBSERVATIONAL
Enrollment

1,000,000

Participants

Timeline

Start Date

November 14, 2024

Primary Completion Date

December 31, 2035

Study Completion Date

December 31, 2045

Conditions
Nasopharyngeal Carcinoma (NPC)Screening
Interventions
DIAGNOSTIC_TEST

EBV antibodies test

ELISA test of VCA-IgA, EBNA1-IgA, EA-IgA, Zta-IgA, Rta-IgG and P85-Ab in nasopharyngeal brushing and plasma in plasma, saliva and nasopharyngeal brushing.

DIAGNOSTIC_TEST

EBV DNA test

quantitative polymerase chain reaction, methylation sequencing and target sequencing of EBV DNA in nasopharyngeal brushing, saliva and plasma.

OTHER

epidemiological information survey

epidemiological information survey including basic conditions, dietary and lifestyle habits, social, geographical, environmental, and other information.

OTHER

Clinical examinations for high-risk participants

nasopharyngoscopy, head and neck MRI.

OTHER

EBV and human genetic sequencing

EB virus and human genetic sequencing for plasma, etc.

Trial Locations (1)

519000

The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai

All Listed Sponsors
collaborator

Fifth Affiliated Hospital, Sun Yat-Sen University

OTHER

collaborator

Sun Yat-sen University

OTHER

lead

Ming-Yuan Chen

OTHER

NCT06787456 - "Xijiang Project Screening Cohort for NPC" | Biotech Hunter | Biotech Hunter