Clinical Impact of Non-invasive Neurally Adjusted Ventilatory Assist in Very Preterm Infants

RecruitingOBSERVATIONAL
Enrollment

80

Participants

Timeline

Start Date

January 20, 2025

Primary Completion Date

December 20, 2029

Study Completion Date

December 20, 2030

Conditions
Preterm Infant
Interventions
PROCEDURE

Non-invasive NAVA

"Initiate respiratory assist with NIV-NAVA within 48 hours. The setting of respiratory support will be adjusted based on clinical conditions of each subject. NIV-NAVA could be switched to nasal continuous airway pressure or high flow nasal cannula, and it also could be stopped after initial stabilization.~In cases of respiratory distress syndrome, lung surfactant will be administered via the less invasive surfactant administration (LISA) method and avoid endotracheal intubation whenever possible. For who intubated in the delivery room, extubation with NIV-NAVA should be considered as soon as possible. Endotracheal intubation with invasive ventilation could be applied when clinical deteriorations happens."

Trial Locations (2)

13620

NOT_YET_RECRUITING

Seoul National Bundang Hospital NICU, Seongnam-si

02841

RECRUITING

Korea University Anam Hospital, NICU, Seoul

All Listed Sponsors
lead

Korea University Anam Hospital

OTHER