"Search for Noninvasive Markers of Graft Injury in Pediatric and Adult Patients With Congenital Heart Disease Undergoing Cardiac Transplantation"

NARecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

March 8, 2023

Primary Completion Date

November 8, 2025

Study Completion Date

March 7, 2026

Conditions
Congenital Heart Disease (CHD)Heart Transplant PatientsAdult Congenital Heart DiseasePediatric Congenital Heart Disease
Interventions
GENETIC

Evaluation of circulating donor free DNA in the recipient's blood (Dd-cfDNA: donor-derived cell free DNA)

From the blood samples taken, 2 mL of plasma separated from blood will be stored in EDTA frozen at -80°C. This material will later be processed by NGS run using of CareDX kits. The result will be provided by dedicated software as percentage of donor DNA in relation to recipient DNA.

Trial Locations (1)

40138

RECRUITING

IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna

All Listed Sponsors
lead

IRCCS Azienda Ospedaliero-Universitaria di Bologna

OTHER