20
Participants
Start Date
January 20, 2025
Primary Completion Date
December 31, 2026
Study Completion Date
December 31, 2027
Avapritinib, azacitidine, Venetoclax
"A: Induction therapy period: After patients were screened and enrolled, they began to receive 1-2 cycles of induction therapy, and the specific administration regimen was as follows: Avapritinib 100mg po qd D1-D14, azacitidine 35mg/m2 ih D1-D5, Venetoclax 100mg po qd D1-D14. The 28-day cycle was followed by curative effect evaluation at the end of each cycle. Patients who achieved complete remission entered the consolidation treatment stage.~B: Consolidation therapy period: Patients who achieved complete remission after 1-2 cycles of induction therapy continued to receive avapritinib 100mg/d po. monotherapy for consolidation therapy, with a cycle of 28 days and a total of 4 cycles"
RECRUITING
Institute of Hematology & Blood Diseases Hospital, Tianjin
Institute of Hematology & Blood Diseases Hospital, China
OTHER